Karen E. Pollok, Ph.D., has been named co-leader of the Experimental and Developmental Therapeutics (EDT) research program.
Pollok’s federally-funded research program intersects with investigators locally and nationally involved in experimental therapeutics for adult and pediatric cancers that encompasses early drug development and repurposing of drugs already in the clinic.
Pollok’s laboratory is identifying risk signatures, biomarkers of therapeutic response, and vulnerabilities in the tumor adaptive response in patients with aggressive solid tumors such as sarcomas and brain tumors.
Pollok, who has been a member of the cancer center since 2001, is an investigator in the Herman B Wells Center for Pediatric Research, associate professor of pediatrics, adjunct associate professor of pharmacology and toxicology, and adjunct associate professor of medical and molecular genetics at IU School of Medicine.
Director of the cancer center’s Preclinical Modeling and Therapeutics Core, she also serves as MPI with Reuben Kapur, Ph.D., of the NIDDK-funded IU Cooperative Centers of Excellence in Hematology. She is a member of the IU Pediatric Molecular Oncology and Experimental Therapeutics research team, and she leads the Sarcoma Translational Research Team, a multidisciplinary working group of trainees, basic researchers, and physician-scientists to foster mentoring, collaboration and translation to the clinic.
Pollok also serves as the co-chair of the Plan to Enhance Diversity (PED) subcommittee at the cancer center. At the national level, she currently serves as a standing member of the NCI Cancer Center Study Section-A Initial Review Group.
Pollok succeeds Xiongbin Lu, Ph.D., and will serve as co-leader with Mat Opyrchal, M.D., Ph.D.