Research Updates

Recent publications

Shahbazi M, Zhang X,Dinh PC, Sanchez VA, Shuey MM, Nguyen T, Regeneron Genetics Center, Feldman DR, Vaughn DJ, Fung C, Kollmannsberger C, Martin NE, Einhorn LH, Cox NJ, Frisina RD, Travis LB, Dolan ED. Comprehensive Association Analysis of Speech Recognition Thresholds after Cisplatin-based Chemotherapy in Survivors of Adult-onset Cancer.  Cancer Med. 2022.  Accepted.

Zhang X, Trendowski MR, Wilkinson E, Shahbazi M, Dinh PC, Shuey MM, Regeneron Genetics Center, Feldman DR, Hamilton RJ, Vaughn DJ, Fung C, Kollmannsberger C, Huddart R, Martin NE, Sanchez VA, Frisina RD, Einhorn LH, Cox NJ, Travis LB, Dolan ME. Pharmacogenomics of Cisplatin-Induced Neurotoxicities: Hearing Loss, Tinnitus and Peripheral Sensory Neuropathy. Cancer Med. 2022. Epub 20220323. doi: 10.1002/cam4.4644. PubMed PMID: 35322580.

Wibmer AG, Dinh PC, Travis LB, Chen C, Bromberg M, Zheng J, Capanu M, Sesso HD, Feldman DR, Vargas HA.  Associations of Body Fat Distribution and Cardiometabolic Risk of Testicular Cancer Survivors After Cisplatin-Based Chemotherapy.  JNCI Cancer Spectr.  2022 Jul 1;6(4):pkac030.  doi: 10.1093/jncics/pkac030. 

Fung C, Dinh Jr P, Travis LB, Commentary, Re: Thyroid hypofunction in aging testicular cancer survivors, Acta Oncologica, 2022 Mar;61(3):386- 387. DOI: 10.1080/0284186X.2021.2024880. Epub 2022 Jan 10. 

Ardeshirrouhanifard S, et al. Ototoxicity After Cisplatin-Based Chemotherapy: Factors Associated With Discrepancies Between Patient-Reported Outcomes and Audiometric Assessments. Ear Hear. 2022 Jan 21. doi: 10.1097/AUD.0000000000001172. Epub ahead of print. PMID: 35067571.

Fung C, Travis LB. (Editorial) Testicular Cancer Survivorship: Looking Back to Move Forward. J Clin Oncol. 2021 Nov 10;39(32):3531-3534. doi: 10.1200/JCO.21.01984. Epub 2021 Sep 30. PMID: 34591594; PMCID: PMC8577670.

Clasen SC, et al. Cisplatin, environmental metals, and cardiovascular disease: an urgent need to understand underlying mechanisms. Cardiooncology. 2021 Oct 10;7(1):34. doi: 10.1186/s40959-021-00120-z. PMID: 34629110; PMCID: PMC8504106.

Ardeshirrouhanifard S,et al. Use of Medications for Treating Anxiety or Depression among Testicular Cancer Survivors: A Multi-Institutional Study. Cancer Epidemiol Biomarkers Prev. 2021 Jun;30(6):1129-1138. doi: 10.1158/1055-9965.EPI-20-1762. Epub 2021 Apr 13. PMID: 33849970; PMCID: PMC8172470. 

Recent presentations

In June 2022, we presented six abstracts at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago:

Nakshatri S, Shuey M, Shahbazi M, Trendowski M, Dinh P, Feldman D, Hamilton R, Vaughn D, Fung C, Kollmansberger C, Einhorn L, Frisina R, Travis LB, Dolan E, Cox N.  Building a model to predict the risk of multiple severe neurotoxicities in cancer survivors after cisplatin treatment. Presented at  ASCO 2022 Annual Meeting, Chicago, IL.  J Clin Oncol 40, 2022 (suppl 16, abstr e24066.  DOI: 10.1200/JCO.2022.40.16_suppl.e24066

Dinh P, Monahan P, Clasen S, Sesso H, Einhorn L, Fossa S, Vaughn D, Martin N, Fung C, Travis LB.  Impact of Adverse Health Outcomes on Self-Reported Physical and Mental Health in U.S. Testicular Cancer Survivors. Presented at ASCO 2022 Annual Meeting, Chicago, IL.  J Clin Oncol 40, 2022 (suppl 16; abstr 12080.  DOI: 10.1200/JCO.2022.40.16_suppl. 12080

Sanchez V, Shuey M, Dinh P, Monahan P, Sesso H, Dolan E, Einhorn L, Vaughn D, Martin N, Fung C, Frisina R, Travis LB.  Impact of Cisplatin-induced Hearing Loss  on Patient-Reported Social and Emotional Functioning. Presented at ASCO 2022 Annual Meeting, Chicago IL.  J Clin Oncol 40, 2022 (suppl 16; abstr 12120).  DOI:  10.1200/JCO.2022.40.16_suppl. 12120

Shuey M, Sanchez V, Dinh P, Monahan P, Sesso H, Dolan E, Einhorn L, Vaughn D, Martin N, Fung C, Frisina R, Travis LB.  Cisplatin-induced Tinnitus and Patient-Reported Outcomes in Adult-Onset Cancer Survivors. Presented at ASCO 2022 Annual Meeting, Chicago, IL.  J Clin Oncol 40, 2022 (suppl 16; abstr e24089).  DOI:  10.1200/JCO.2022.40.16_suppl.e24089

Zheng Y, Wang J, Dinh P, Nathanson K, Weathers B, Jacobs L, Vaughn D, Hou L, Travis LB.  Epigenetic Age Acceleration in  U.S. Testicular Cancer Survivors. Presented at ASCO 2022 Annual Meeting, Chicago, IL.  J Clin Oncol 40, 2022.  Suppl 16; abstr 5033  DOI:  10.1200/JCO.2022.40.16_suppl. 5033

Miller M, Ashkar R, Althouse S, Hanna N, Abonour R, Travis LB, Einhorn L, Adra N, Abu Zaid M.  Adverse health outcomes  in testis cancer survivors following high dose chemotherapy  and autologous stem cell transplant. Presented at ASCO 2022 Annual Meeting, Chicago, IL.  J Clin Oncol 40, 2022 (suppl 16; abstr 12083).  DOI: 10.1200/JCO.2022.40.16_suppl. 12083

In June 2021, we presented five abstracts at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago:

Shuey, et al. Integration of a polygenic risk score of kidney function with cumulative cisplatin dose and time variables for the prediction of serum platinum levels.J Clin Oncol 39, 2021 (suppl 15; abstr 12063). doi:J Clin Oncol 39, 2021 (suppl 15; abstr 12063).

Zhang, et al. Pharmacogenomics of cisplatin-induced neurotoxicities: Hearing loss, tinnitus and peripheral sensory neuropathy. J Clin Oncol 39, 2021 (suppl 15; abstr 12004). doi:10.1200/JCO.2021.39.15_suppl.12004.

Ardeshirrouhanifard, et al. Hearing Loss after Cisplatin-based Chemotherapy: Patient-reported Outcomes versus Audiometric Assessments. J Clin Oncol 39, 2021 (suppl 15; abstr 5016). doi:10.1200/JCO.2021.39.15_suppl.5016.

Ardeshirrouhanifard, et al. Factors associated with use of medications for anxiety and depression in testicular cancer survivors after cisplatin-based chemotherapy. J Clin Oncol 39, 2021 (suppl 15; abstr 5025). doi:10.1200/JCO.2021.39.15_suppl.5025.

Wibmer AG, Feldman DR, Chen C, Bromberg M, Dinh PC, Zheng J, Capanu M, Travis LB, Vargas HA. Effect of pretreatment central adiposity on the cardiometabolic risk of male germ cell tumor survivors after cisplatin-based chemotherapy. Journal of Clinical Oncology. 2021;39(15_suppl):5019-. doi: 10.1200/JCO.2021.39.15_suppl.5019.

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