Scientists at Indiana University and the Brown Center for Immunotherapy are developing cutting-edge research. The Cell & Gene Therapy Manufacturing team is poised to translate this research into investigational products used to treat patients in clinical trials.
Translating our research for our patients
Services and technology
The Cell & Gene Therapy Manufacturing team provides translational and manufacturing services to enable early-phase cell and gene therapy trials. This team includes scientific and technical staff, quality assurance staff, facility and operations staff, and business staff.
- We have a Bioprocess Development Laboratory for scale-up, translation, and optimization of vector and cell processing techniques.
- The Vector Production Facility is an ISO class 7 clean room facility that manufactures lentiviral and retroviral vector products and master cell banks for early-phase trials.
- Our Cell Immunotherapy & Transduction Facility features an ISO class 7 clean room facility and a quality control testing laboratory that manufactures and performs quality control testing on cellular products for clinical trials.
- Preclinical study design and reagents
- IND Support: chemistry, manufacturing, and control
- Feasibility studies and engineering studies
- Grant support: projects and budgets
- Technology transfer
- Process development
- Analytical development
- Scale up/scale out
- Preclinical vector manufacturing
- Master cell banks for retroviral vectors
- Retroviral vectors
- Lentiviral vectors
- Cell activation and expansion
- Cell enrichment
- Genetic modification
- Automated cell processing
- Formulation and cryopreservation
- Product testing and release
Meet our team
Questions?
For more information, contact Emily Hopewell, PhD, facility director, at emlhope@iu.edu or (317) 278-1109.
