8:30 – 9:10 AM | Registration and Continental Breakfast (Joseph Walther Hall Atrium, 2 nd floor) |
9:10 – 9:15 AM | Welcome Remarks
Mark Kelley, PhD Betty and Earl Herr Professor of Pediatric Oncology Research Associate Director, Indiana University Melvin and Bren Simon Comprehensive Cancer Center Professor of Pediatrics Professor of Biochemistry & Molecular Biology Professor of Pharmacology & Toxicology Professor of Ophthalmology IU School of Medicine |
9:15 – 9:45 AM | Ashiq Masood, MD Associate Professor of Medicine, Division of Hematology/Oncology IU School of Medicine
"Navigating the Pancreatic Cancer Mosaic: Illuminating Cancer's Spatial Dynamics Through Transcriptomic Atlases”
Introduction: Mark Kelley, PhD |
9:45 – 10:15 AM | Rajesh Sardar, PhD Professor of Chemistry and Chemical Biology School of Science at Indiana University Indianapolis
“Predictive circulating biomarker levels for early diagnosis and treatment response of pancreatic malignancy”
Introduction: Melissa Fishel, PhD |
10:15 – 10:30 AM | Coffee Break |
10:30 – 11 AM | TRAINEE TALKS - Selected from abstract submissions
10:30-10:40 am - Investigating the role of Krüppel-Like Factor 10 (KLF10) in Pancreatic Ductal Adenocarcinoma (PDAC) associated cachexia Savannah Epstein, PhD Student
10:40-10:50 am - Impact of genetic alterations in Ref-1 using CRISPR editing of cysteine residues (C65, C93, C99) on redox signaling, proliferation and metastasis in pancreatic cancer Hayati Laleh Sanya, Postdoctoral Fellow
10:50-11:00 am - Synergistic effects of PARP inhibitor Rucaparib and the novel NQO1 bioactivatable drug IP-DNQ in targeting NQO1-positive pancreatic cancer: Mechanistic insights and therapeutic potential Soumya Tumbath, Postdoctoral Fellow
Moderated by: Jason Doles, PhD |
11 AM – 12 PM | KEYNOTE ADDRESS
Jen Jen Yeh, MD Professor of Surgery and Pharmacology University of North Carolina (UNC) at Chapel Hill Vice Chair of Research Co-Director of Clinical Research UNC Lineberger Comprehensive Cancer Center
“Implications of molecular subtypes in pancreatic cancer”
Introduction: Brittany Allen-Petersen, PhD |
12 – 12:55 PM | Lunch (attendees will be escorted to 3 rd floor) Walther Hall (R3) 303-305 |
1 – 2 PM | RISING STAR/KEYNOTE ADDRESS
Kirsten Bryant, PhD Assistant Professor of Pharmacology University of North Carolina (UNC) at Chapel Hill UNC Lineberger Comprehensive Cancer Center
“Elucidation of metabolic resistance mechanisms to RAS inhibition”
Introduction: Mark Kelley, PhD |
2 – 2:15 PM | Anita Turk, MD Assistant Professor of Clinical Medicine IU School of Medicine
“State of Affairs for Therapeutics for PDAC” Introduction: Melissa Fishel, PhD |
2:15 – 2:55 PM | Patient Perspectives
Patient Advocate - Dwayne Montgomery Patient Advocate - Ellen Miller Moderated by: Brittany Allen-Petersen, PhD |
2:55 – 3:20 PM | PANEL – Clinical Perspectives
Michael House, MD (moderator) Professor of Surgery Chief, Division of Surgical Oncology IU School of Medicine Co-Director of Pancreatic Cancer Program Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Fatih Akisik, MD Professor of Clinical Radiology and Imaging Sciences Director of Clinical MR Imagine IU School of Medicine
Harvey Cramer, MD Associate Professor of Pathology and Laboratory Medicine Director of Cytopathology IU School of Medicine
Jeffrey Easler, MD Associate Professor of Medicine and Gastroenterology Director of Advanced Endoscopy Fellowship Program IU School of Medicine
Robert Miller, MD Clinical Professor of Radiation Oncology IU School of Medicine
Alexandra Roch, MD Assistant Professor of Surgery IU School of Medicine Co-Director of the IU Pancreas Cyst and Cancer Early Detection Program Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Omer Saeed, MD Assistant Professor of Pathology and Laboratory Medicine Section Head of Gastrointestinal Pathology IU School of Medicine
Anita Turk, MD Associate Professor of Clinical Medicine and Medical Oncology IU School of Medicine Co-Director of Pancreatic Cancer Program Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Moderated by: Michael House, MD |
3:20 – 3:30 PM | Closing Remarks
Melissa Fishel, PhD Associate Professor of Pediatrics, Herman B Wells Center for Pediatric Research Associate Professor of Pharmacology & Toxicology IU School of Medicine Myles Brand Scholar in Cancer Research Indiana University Melvin and Bren Simon Comprehensive Cancer Center |