Andrea Gianaris Pancreatic Cancer Symposium

Gianaris Symposium

The objectives of the Gianaris Pancreatic Cancer Symposium, hosted by the IU Simon Comprehensive Cancer Center, are:

  • Describe management for patients with pancreatic cancer based on novel and exciting basic science research
  • Discuss "best" clinical practice guidelines
  • Recognize management options for patients with pancreatic cancer

Dr. Peter Gianaris, a neurosurgeon with Goodman-Campbell, established the symposium in memory of his wife, Andrea, in 2012.

Agenda

 8:30 – 9:10 AM

Registration and Continental Breakfast

(Joseph Walther Hall Atrium, 2 nd floor)

 9:10 – 9:15 AM

Welcome Remarks

Mark Kelley, PhD
Betty and Earl Herr Professor of Pediatric Oncology Research
Associate Director, Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Professor of Pediatrics
Professor of Biochemistry & Molecular Biology
Professor of Pharmacology & Toxicology
Professor of Ophthalmology
IU School of Medicine

 9:15 – 9:45 AM

Ashiq Masood, MD
Associate Professor of Medicine, Division of Hematology/Oncology
IU School of Medicine

"Navigating the Pancreatic Cancer Mosaic: Illuminating Cancer's Spatial Dynamics Through Transcriptomic Atlases”

Introduction: Mark Kelley, PhD      

 9:45 – 10:15 AM

Rajesh Sardar, PhD
Professor of Chemistry and Chemical Biology
School of Science at Indiana University Indianapolis

“Predictive circulating biomarker levels for early diagnosis and treatment response of pancreatic malignancy”

Introduction: Melissa Fishel, PhD

10:15 – 10:30 AM

Coffee Break

10:30 – 11 AM

TRAINEE TALKS - Selected from abstract submissions


10:30-10:40 am - Investigating the role of Krüppel-Like Factor 10 (KLF10) in Pancreatic Ductal Adenocarcinoma (PDAC) associated cachexia       Savannah Epstein, PhD Student


10:40-10:50 am - Impact of genetic alterations in Ref-1 using CRISPR editing of cysteine residues (C65, C93, C99) on redox signaling, proliferation and metastasis in pancreatic cancer     Hayati Laleh Sanya, Postdoctoral Fellow  


10:50-11:00 am - Synergistic effects of PARP inhibitor Rucaparib and the novel NQO1 bioactivatable drug IP-DNQ in targeting NQO1-positive pancreatic cancer: Mechanistic insights and therapeutic potential     Soumya Tumbath, Postdoctoral Fellow


Moderated by: Jason Doles, PhD

11 AM – 12 PM

KEYNOTE ADDRESS

Jen Jen Yeh, MD
Professor of Surgery and Pharmacology
University of North Carolina (UNC) at Chapel Hill
Vice Chair of Research
Co-Director of Clinical Research
UNC Lineberger Comprehensive Cancer Center

Implications of molecular subtypes in pancreatic cancer

Introduction: Brittany Allen-Petersen, PhD

 12 – 12:55 PM

Lunch (attendees will be escorted to 3 rd floor)

Walther Hall (R3) 303-305

 1 – 2 PM

RISING STAR/KEYNOTE ADDRESS

Kirsten Bryant, PhD
Assistant Professor of Pharmacology
University of North Carolina (UNC) at Chapel Hill
UNC Lineberger Comprehensive Cancer Center

“Elucidation of metabolic resistance mechanisms to RAS inhibition”

Introduction: Mark Kelley, PhD

 2 – 2:15 PM

Anita Turk, MD
Assistant Professor of Clinical Medicine
IU School of Medicine

“State of Affairs for Therapeutics for PDAC”

Introduction: Melissa Fishel, PhD

2:15 – 2:55 PM

Patient Perspectives

Patient Advocate - Dwayne Montgomery
Patient Advocate - Ellen Miller

Moderated by: Brittany Allen-Petersen, PhD

2:55 – 3:20 PM

PANEL – Clinical Perspectives

Michael House, MD (moderator)
Professor of Surgery
Chief, Division of Surgical Oncology
IU School of Medicine
Co-Director of Pancreatic Cancer Program
Indiana University Melvin and Bren Simon Comprehensive Cancer Center

Fatih Akisik, MD
Professor of Clinical Radiology and Imaging Sciences
Director of Clinical MR Imagine
IU School of Medicine

Harvey Cramer, MD
Associate Professor of Pathology and Laboratory Medicine
Director of Cytopathology
IU School of Medicine

Jeffrey Easler, MD
Associate Professor of Medicine and Gastroenterology
Director of Advanced Endoscopy Fellowship Program
IU School of Medicine

Robert Miller, MD
Clinical Professor of Radiation Oncology
IU School of Medicine

Alexandra Roch, MD
Assistant Professor of Surgery
IU School of Medicine
Co-Director of the IU Pancreas Cyst and Cancer Early Detection Program
Indiana University Melvin and Bren Simon Comprehensive Cancer Center

Omer Saeed, MD
Assistant Professor of Pathology and Laboratory Medicine
Section Head of Gastrointestinal Pathology
IU School of Medicine

Anita Turk, MD
Associate Professor of Clinical Medicine and Medical Oncology
IU School of Medicine
Co-Director of Pancreatic Cancer Program
Indiana University Melvin and Bren Simon Comprehensive Cancer Center

Moderated by: Michael House, MD

 3:20 – 3:30 PM

Closing Remarks

Melissa Fishel, PhD
Associate Professor of Pediatrics, Herman B Wells Center for Pediatric Research
Associate Professor of Pharmacology & Toxicology
IU School of Medicine
Myles Brand Scholar in Cancer Research
Indiana University Melvin and Bren Simon Comprehensive Cancer Center

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