Investigator-Initiated Trials

The application should be a maximum of three pages.

• Study title
• Key collaborators
• Scientific rationale
• Hypothesis
• Objectives
• Patient population (major criteria only)
• Treatment or intervention
• Statistical plan and sample size justification
• Embedded correlatives/biomarkers
• References (not included in page limit) 

Input from the Translational Research Core is strongly encouraged.

• NIH biosketch (PI and key collaborators only).
• Budget and total funding requested.
• Other support available for this proposed trial.
• Letter from division chief or department head confirming that no start-up or discretional funds are available.
• Commitment to external funding – if submitted and not funded, please provide prior reviews. What are your plans for external funding and how will this support increase your chances of success?

Evaluation criteria will include:

• Scientific merit
• Novelty
• Strength of collaboration
• Potential for external funding

Please submit applications to Mario Contreraz at contrmar@iu.edu.

• Applications will be accepted on a rolling basis with funding decisions made quarterly (September, December, March, June) by the IUSCCC Executive Committee.
• Please do not submit the full protocol. Applications can be submitted at any time during the protocol development process, but early application is encouraged to avoid delays.
• Trials approved by the SRC without funding will be placed on administrative hold until support is obtained.
• Funding will be limited to support CTO services.