Cancer Prevention & Control

Cancer Prevention LabCancer Prevention and Control (CPC) researchers are engaged in innovative and collaborative research with the potential to decrease cancer morbidity and mortality. CPC researchers are also involved in prevention and early detection of cancer through cancer risk reduction and screening as well as preventing and reducing debilitating symptoms caused by cancer treatment while tailoring interventions to individuals. The program’s themes focus on two crucial challenges across the cancer continuum: 1.) preventing the occurrence of cancer and detecting it early whenever possible by increasing the effectiveness and adherence to cancer screening; and 2.) identifying mechanisms of treatment-related toxicities (neuropathy and cognitive dysfunction) and developing interventions to improve the quality of cancer care, including supportive care, and reducing symptom burden from cancer therapies.

Scientific goals: The scientific goals of the program are advanced by focused work in two themes:

Theme 1: Prevention and early detection

Risk factors: Identify cancer risk factors, including genetic susceptibility and molecular subtypes of cancer.

Mechanisms: Create and translate risk models for cancer that enable clinicians and patients to make informed and shared screening decisions.

Interventions: Test cost-effective ways to translate efficacious interventions for cancer risk reduction, screening and follow-up.

Theme 2: Survivorship and supportive care

Risk factors: Identify genetic susceptibility and biomarkers of treatment-related toxicities.

Mechanisms: Identify mechanisms, prevention and treatment of chemotherapy-induced cognitive dysfunction and peripheral neurotoxicity.

Interventions: Test interventions to improve quality of cancer care, including supportive care and reduce symptoms among survivors.