Feature – 2022 ASH

By Candace Gwaltney

Dec. 8, 2022

Indiana University Melvin and Bren Simon Comprehensive Cancer Center researchers are authors on more than 35 research studies that are part of the 64th American Society of Hematology (ASH) Annual Meeting. The world’s largest hematology event, ASH brings together more than 20,000 hematology professionals. This year’s event is Dec. 10-13 in New Orleans.

Findings on multiple myeloma, CAR T-cell therapy, acute myeloid leukemia, Hodgkin lymphoma and sickle cell disease are among the abstracts by cancer center members. 

Highlights include: 

• Single Cell Multiomic Analysis Reveals Relapsed and Refractory Multiple Myeloma Cells Associated with 1q, TP53, and PHF19 alterations That Affect Subclonal Chromatin Accessibility
  Travis S. Johnson, Ph.D., will share these finding during an oral presentation.
  Additional IU authors: Parvathi Sudha, M.S., Enze Liu, Ph.D., Kun Huang, Ph.D., Rafat Abonour, M.D., Mohammad Issam Abu Zaid, M.D., and Brian A. Walker, Ph.D.
• A Novel Bi-Specific T-Cell Engager Targeting ILT3 Is Potently Effective in Multiple Myeloma
  Francesco Di Meo, Ph.D., a postdoctoral fellow conducting research in the lab of Fabiana Perna, M.D., Ph.D., will share these findings during an oral presentation.
  Additional IU authors: Christina Yu, Annamaria Cesarano, Silvia Marino, Ph.D., Arafat Aljoufi, M.D., Kun Huang, Ph.D., David G. Roodman, M.D., Ph.D. and Fabiana Perna, M.D., Ph.D.
• Rare and Unique Presentations of ICANS and On-Target/Off-Tumor Toxicity Considerations, Symposia: Scientific Workshop on Bedside to Bench.
  Fabiana Perna, M.D., Ph.D., will moderate this session and will present “Novel Targets and Off-Tumor Toxicities.”

Additional cancer center members and  IU School of Medicine researchers with research findings at this year’s ASH include: Nathan Becker, M.S.; Jennifer Belsky, DO, M.S.; Sanam Rezaei Benam, M.Sc.; Kinjal Bhadresha, Ph.D.; H. Scott Boswell, M.D.; Maegan L. Capitano, Ph.D.; Ka-Kui Chan, Ph.D.; John Chirgwin, Ph.D.; D. Wade Clapp, M.D.; Kenneth Cornetta, M.D.; Colin D. Crean, B.S.; Larry D. Cripe, M.D.; Magdalena Czader, M.D., Ph.D.; Utpal Dave, M.D.; Alexander R. Maldeney, BSc; Chuanpeng Dong, Ph.D.; Sherif S Farag, M.D., Ph.D.; Maggie Granatir, B.S.; Monica L. Guzman, Ph.D.; David Halladay, Ph.D.; Jie Jiang, Ph.D.; Mark Kaplan, Ph.D.; Reuben Kapur, Ph.D.; Kelvin P. Lee, M.D.; Yunlong Liu, Ph.D.; Sheng Liu, Ph.D.; Jagannath Misra, Ph.D.; Grzegorz Nalepa, M.D., Ph.D.; Lakshmi Reddy Palam, Ph.D.; Katelyn Pickerell; Karen E. Pollok, Ph.D.; Elizabeth Sierra Potchanant, Ph.D.; Baskar Ramdas, Ph.D.; George E. Sandusky, DVM, Ph.D.; Reza Shahbazi, Ph.D.; Aditya S. Sheth, M.Sc.; Anthony L. Sinn, B.S., LAT; Jodi L. Skiles, M.D.; Sankalp Srivastava, M.S.; Attaya Suvannasankha, M.D.; Terry Vik, M.D.; Jun Wan, Ph.D.; Ronald Wek, Ph.D.; Xiaoling Xuei, Ph.D.; Ji Zhang, Ph.D.; Shuhong Zhang, Ph.D.; and Jiehao Zhou, M.D.