Tyler Shugg, Ph.D.
950 W. Walnut Street
Indianapolis, IN 46202
Phone: (317) 278-3054
Research Program Membership
Assistant Research Professor
Department of Medicine
Division of Clinical Pharmacology
IU School of Medicine
Dr. Shugg's research interests include:
My overarching research interests are to employ precision medicine approaches to improve medication outcomes in patients with cancer. My research directions include projects related to precision medicine discovery (i.e., identifying novel applications for precision medicine in cancer patients) and precision medicine implementation (i.e., implementing clinical interventions to translate existing knowledge in order to benefit patients). My primary independent discovery project is to investigate the potential for novel immune-related drug-drug interactions with immune checkpoint inhibitors and co-administered Cytochrome P450 substrate medications. Towards this project, I have foundation grant and NIGMS K23 applications currently under review. My primary implementation project is to develop computational methods to repurpose genomic sequencing data (as is obtained for tumor board patients) to support germline pharmacogenetics for cancer therapies (fluoropyrimidines, thiopurines) and supportive therapies (antiemetics, analgesics, antidepressants, etc.). In the future, I also plan to collaborate with the pharmacy team at IUSCC to incorporate pharmacogenetic results into current medication therapy management/ medication reconciliation clinical services.
Post-doctoral Fellowship - Indiana University School of Medicine, Indianapolis, IN 12/2021
Post-doctoral Fellowship - University of Michigan, Ann Arbor, MI 08/2019
Ph.D. - Purdue University, West Lafayette, IN 08/2018
Pharm.D. - Purdue University, West Lafayette, IN 05/2013