My lab is focused on mechanisms that control adipose tissue homeostasis in response to physiologic challenges and pathological conditions. As obesity is one of the significant contributors to cancer, I have been always interested in how these pathological states interact with each other, which has been also a hot topic in cancer biology fields. We have recently become interested in the mechanisms by which adipose tissue is remodeled during cancer progression. We have thus initiated the collaboration with Dr. Teresa Zimmers to understand how adipose tissue homeostasis is altered in the context of pancreatic cancer cachexia by using our expertise in transcriptomic and epigenomic profiling techniques. Specifically, we will employ our state-of-the-art single nucleus RNA-seq to elucidate dynamic changes in adipose tissue cell populations from mouse models of pancreatic cancer cachexia. In the future, we plan to expand our studies to other types of cancer and to further investigate the reciprocal interaction between adipose tissues and cancer.
Post-doctoral Fellowship - Washington University, St. Louis, MO 2011-2012
Post-doctoral Fellowship - Beth Israel Deaconess Medical Center, Boston, MA 08/2019
Ph.D. - Washington University, St. Louis, MO 08/2011
