Member Biography

Khalid Said Mohammad

Khalid Mohammad, M.D., Ph.D.

980 W Walnut St.
R3 C124
Indianapolis, IN 46202
Phone: (317) 278-6013
Fax: (317) 278-2912

Research Program Membership

Full member

Senior Research Professor of Medicine
Department of Medicine
Division of Endocrinology
IU School of Medicine

Adjunct Senior Research Professor of Anatomy & Cell Biology
Department of Anatomy and Cell Biology
IU School of Medicine

My main interest is in bone histomorphometry and mouse imaging component for the bone and bone metastases as well as developing mouse tumor models. The specialized methods of bone study employed include evaluation of bone histology samples, performing bone histomorphometry, assessing bone mineral density using DXA scans, analyzing radiographic images of research samples as well as setting bone cell culture. I extensively use animal models of bone metastases, testing various clinically approved drugs, or drugs that are in clinical trials, in animal models of bone metastases. These studies have included testing the effect of an endothelin A receptor antagonist in mouse model of osteoblastic breast cancer bone metastases. I have tested a p38 MAPK inhibitor in several models of cancer including breast and prostate cancer. I have extensively tested a TGF beta receptor I kinas inhibitor (SD-208) alone and in combination with bisphosphonates in models of prostate cancer, breast cancer and melanoma. In collaboration with Dr. Francis Shen an orthopaedic surgeon at University of Virginia we worked on developing a rat model of spine metastases, this wrok is published in the Journal "Spine". In collaboration with Dr. Alain Mauviel at the INSERM institute, Paris, France, we developed a new animal model of melanoma bone metastases.

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Ph.D. - University of South Dakota, Vermillion, SD 2000

Post-doctoral Fellowship - University of Texas Health Science Center, San Antonio, TX 200-2002

M.Sc. - University of London, UK 1992

M.D. - Ain shams University, Cairo Egypt 1987