Carlos Serenzani, Ph.D.
950 W. Walnut St.
Indianapolis, IN 46202
Phone: (317) 278-0100
Fax: (317) 274-7592
Research Program Membership
Department of Microbiology and Immunology
My current research interest deals with the role of the phohsphatase and tensin homolog PTEN in the regulation of transcriptional machinery involved in microRNA synthesis in macrophages. Our preliminary data show that PTEN inhibits the expression of the inflammatory adaptor MyD88. MyD88 is utilized by IL-1R family and pathogen recognition receptors, such as toll like receptors. Our project exhibits high relevance to Cancer biology, since we are studying the role of the tummor suppressor PTEN in the control of emerging tumor regulators microRNAs.
Fellowship - University of Michigan, Ann Arbor, MI 2006
Ph.D. - University of Sao Paulo, Sao Paulo, Brazil 2005