Member Biography

Carlos Serenzani, Ph.D.

950 W. Walnut St.
R2 280
Indianapolis, IN 46202

Phone: (317) 278-0100
Fax: (317) 274-7592

Research Program Membership

Assistant Professor
Department of Microbiology and Immunology

My current research interest deals with the role of the phohsphatase and tensin homolog PTEN in the regulation of transcriptional machinery involved in microRNA synthesis in macrophages. Our preliminary data show that PTEN inhibits the expression of the inflammatory adaptor MyD88. MyD88 is utilized by IL-1R family and pathogen recognition receptors, such as toll like receptors. Our project exhibits high relevance to Cancer biology, since we are studying the role of the tummor suppressor PTEN in the control of emerging tumor regulators microRNAs.

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More Publications »

Fellowship - University of Michigan, Ann Arbor, MI 2006

Ph.D. - University of Sao Paulo, Sao Paulo, Brazil 2005