Inclusion Criteria:
- ECOG 0-1
- Histologically or cytologically confirmed diagnosis of endometrial cancer documented
as TP53WT
- Subjects with advanced or recurrent disease must have completed a single line of up to
6 cycles of taxane-platinum based chemo and achieved a CR or PR per RECIST V1.1
- Adequate hematologic, hepatic and renal function (within 14 days)
Exclusion Criteria:
- Has any sarcomas or small-cell carcinomas with neuroendocrine differentiation
- Prior immune therapy, cytokine therapy, or any investigational therapy (within 28
days)
- Indwelling surgical drains
- Grade 2 or higher QTc prolongation
- History of major organ transplant
- History of bleeding diathesis; major hemorrhage or intracranial hemorrhage (within 24
weeks)