Inclusion Criteria:
* Men diagnosed with prostate cancer who choose radical prostatectomy
* Significant prostate cancer: Gleason 3+4 ≥1 core with pattern 4 ≥20% OR ≥3 cores of Gleason 3+4 OR Any Gleason 4+3, 4+4, 4+5, 5+4, or 5+5 AND
* Baseline sexual function (IIEF-EF ≥ 17): No erectile dysfunction OR mild erectile dysfunction OR mild-to-moderate erectile dysfunction (International Index of Erectile Function-Erectile Function domain ≥ 17). AND
* The patient desires to maintain erections following treatment.
Exclusion Criteria:
* Participation in another investigational trial involving research exposure to ionizing radiation concurrently or within 30 days
* Patient is unable to tolerate remaining still on the bed of the PET or MRI camera, due to physical limitations or claustrophobia.
* c. Significant acute or chronic medical condition in the subject that could compromise the objectives of the study.