Inclusion Criteria:
- Men diagnosed with prostate cancer who choose radical prostatectomy
- Significant prostate cancer: Gleason 3+4 ≥1 core with pattern 4 ≥20% OR ≥3 cores of
Gleason 3+4 OR Any Gleason 4+3, 4+4, 4+5, 5+4, or 5+5 AND
- Baseline sexual function (IIEF-EF ≥ 17): No erectile dysfunction OR mild erectile
dysfunction OR mild-to-moderate erectile dysfunction (International Index of Erectile
Function-Erectile Function domain ≥ 17). AND
- The patient desires to maintain erections following treatment.
Exclusion Criteria:
- Participation in another investigational trial involving research exposure to ionizing
radiation concurrently or within 30 days
- Patient is unable to tolerate remaining still on the bed of the PET or MRI camera, due
to physical limitations or claustrophobia.
- c. Significant acute or chronic medical condition in the subject that could compromise
the objectives of the study.