Glioblastoma is a type of brain cancer that is extremely dangerous. Unfortunately, it tends to come back even after treatment because there are specific cells in the tumors called glioblastoma stem cells (GSCs) that are very tough and can resist common cancer treatments like chemotherapy and radiotherapy. These cells have special abilities that help them stay dormant and multiply, making it difficult to eliminate them completely. In our research, currently we’re trying to find a way to effectively kill these GSCs by using a “one-two punch” strategy. First, we want to block their ability to keep renewing themselves, essentially stopping them from growing and spreading. Second, we aim to activate the immune system to attack and destroy these cancer stem cells. By combining these two aspects, we hope to deliver a powerful blow to the GSCs and improve the chances of successfully treating glioblastoma.
Post-doctoral Fellowship - Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 2015-2020
Ph.D. - Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, China 2014