My long-term career aspiration is to focus my research initiatives toward the development of novel, personalized therapies for pediatric solid tumors. my research efforts have been focused on identifying the overlap and connecting the bioinformatics-based large-scale genomic findings with clinically defined prognostic/predictive epigenetic biomarkers, such as EZH2 and its methylated targets in Ewing’s Sarcoma as well as bromodomain-mediated recognition of acetylated epigenetic marks on target genes in Osteosarcoma for preclinical functional validation. Investigating and targeting such therapeutic resistant mechanisms could significantly impact the dismal prognosis we see in pediatric patients with relapsed/recurrent cancers.
Post-doctoral Fellowship - Indiana University School of Medicine, Indianapolis, IN 10/2015
Ph.D. - Indiana University-Purdue University, Indianapolis, IN 08/2010