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Member Biography

April L Rahrig, DO

April L Rahrig, DO

Phone: (317) 278-3014

705 Riley Hospital Drive
RI 4340
Indianapolis, IN 46202
Fax: 317-944-3107

Faculty appointments

Assistant Professor of Pediatrics, Department of Pediatrics, Division of Hematology/Oncology, IU School of Medicine
Associate member, Hematopoiesis & Hematologic Malignancies

My current research explores the complications of stem cell transplant and CAR-T Cell therapy and how best to treat these conditions. Some of the complications I am researching include: pneumatosis intestinalis, diffuse alveolar hemorrhage, thrombotic microangiopathy, veno occlusive disease, and graft versus host disease. I have collaborated with the pediatric intensive care team to help identify biomarkers for some of these conditions and describing pathways to diagnose these conditions earlier and standardize their treatment. In the future I am interested in growing my multi-institutional collaborations to further expand my research in these areas.

A phase II trial of tisagenlecleucel in first-line high-risk (HR) pediatric and young adult patients with B-cell acute lymphoblastic leukemia (B-ALL) who are minimal residual disease (MRD) positive at the end of consolidation (EOC) therapyPHO-NOVARTIS-CCTL019G2201J

A Phase 1/2 Multi-Center Trial of Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow TransplantationPHO-UMICH-VORINOSTAT

A Multi-Center, Phase 3, Randomized Trial of Matched Unrelated Donor (MUD) versus HLA-Haploidentical Related (Haplo) Myeloablative Hematopoietic Cell Transplantation for Children, Adolescents, and Young Adults (AYA) with Acute Leukemia or Myelodysplastic Syndrome (MDS)PHO-COG-ASCT2031

A Phase 1 Trial of Targeted Immunotherapy with Daratumumab Following Myeloablative Total Body Irradiation (TBI)-Based Conditioning and Allogeneic Hematopoietic Cell Transplantation in Children, Adolescents and Young Adults with High-Risk T-Cell Acute Lymphoblastic Leukemia and LymphomaPHO-NYMC-ALLO-T-DART

Assessing the utility of ammonia levels as a tool for veno-occlusive disease (VOD) diagnosis.PHO-IIR-IUSCC-0728

Letermovir Prophylaxis for Cytomegalovirus in Pediatric Hematopoietic Cell TransplantationPHO-COG-ACCL1932

Pneumatosis intestinalis following hematopoietic stem cell transplant: clinical outcomes, risk factors, and interventions in the pediatric populationPHO-IIR-PI-POST-HSCT

A Retrospective Study of Contemporary Approaches to First Relapse in B-ALL (RECALL-1)PHO-CHOP-RECALL-1

Multicenter Retrospective Review of BAL in Pediatric HSCT patientsPHO-IIR-20626

Outcomes in Juvenile Myelomonocytic Leukemia Patients Undergoing Hematopoietic Stem Cell Transplantation By Donor TypePHO-IIR-JMML-AHCT

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