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Trial Summary

Protocol No.CTO-IUSCCC-0747
Principal InvestigatorSaito, Naoyuki
PhasePhase I/II
Age GroupAdult
TitleA Dose Escalation Study of Intensity Modulated Total Marrow Irradiation (IMRT-TMI) followed by Fludarabine as a Myeloablative Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Relapsed and Refractory Hematologic Malignancies
Key EligibilityIn order to be eligible to take part in this trial, patients must meet the following criteria:
  • The patient must be 18-65 years old at time of consent
  • Availability of a consenting human leukocyte antigens (HLA)-matched donor
  • Acute Myeloid Leukemia (AML), with no history of extramedullary disease, who are not in complete remission, who have either primary refractory or relapsed disease
  • Karnofsky Performance Status 70% or higher
For a full list of participation criteria, please visit
Applicable Disease SitesLeukemia, other
Participating InstitutionsIndiana University (IU)
    Treatment TypeTreatment
    ContactPhone: (317) 278-5632