IU Genome Editing Center


The IUGEC offers three categories of services:

  • Model generation services (the core oversees and performs every step of the process and delivers fully-vetted models to investigators).
  • A la carte solutions (the core performs select procedures for the generation of animal models).
  • Technology development (the core works in collaboration with investigators to develop or implement new genome editing technologies).

Model generation services include:

  • The generation of genetically modified mouse models.
  • The generation of genetically modified cell line models (transformed cell lines, murine stem cells and human induced pluripotent stem cells.

A la carte solutions include:

  • Pronuclear injection of C57BL/6 mice
  • Sperm cryopreservation with verification
  • Sperm cryopreservation without verification
  • In vitro fertilization and embryo transfer
  • Embryo thaw and transfer

Technology development:

  • For technology development, please contact the core director, Stephane Pelletier (spellet@iu.edu).