The long-term goal of my research program is to understand the cellular and molecular mechanisms underlying neuroimmune and neurovascular interactions in brain injury and how they contribute to the onset and severity of Alzheimer’s disease and related dementias (ADRD). Current projects in my laboratory focus on the role of alkaline phosphatases at the blood-brain barrier and gut-vascular barrier in animal models of ischemic stroke, sepsis, and Alzheimer's disease. Another area of interest in my laboratory is the identification of extracellular vesicle biomarkers in patients with silent stroke/silent brain infarction and acute ischemic stroke. Ongoing and future cancer-related projects in the laboratory will focus on the role of brain microvascular dysfunction in cancer-related cognitive impairment (CRCI) and endothelial extracellular vesicles as plasma biomarkers for CRCI.
Post-doctoral Fellowship - University of Washington, Seattle, WA 2011
Post-doctoral Fellowship - University of California, Davis, CA 2005
Ph.D. - Duke University, Durham, North Carolina 2004
