Chemical Genomics
Rapid advances in life sciences are uncovering an increasing number of
molecular targets relevant to many human diseases including cancer. The Chemical Genomics Core Facility was established to facilitate the discovery of small molecule tools for biological pathway analysis and for therapeutic development. Molecule tools can be very important in the development of therapeutic agents since they can be used to test the effects of altering biological processes in cells, which can lead to the identification of validated targets for drug development.
The mission of the Chemical Genomic Core is to provide Indiana University investigators with cost-effective access to high throughput screening of small molecules in biological assays. This enables investigators to discover small molecule tools for basic research, therapeutic development and diagnostic applications, and also provide an opportunity for IU students and fellows to gain experience and training in high throughput screening at the facility.
The Chemical Genomics Core Facility is equipped with automated liquid handling and assay detection instrumentation; structurally-diverse, drug-like small molecule libraries; and a staff experienced in assay development, high throughput screening and laboratory robotics.
For more information, visit the Chemical Genomics Core Facility Web site.