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Trial Summary

Protocol No.CANSTEM111P
Principal InvestigatorO'Neil, Bert
PhasePhase III
Age GroupAdult
TitleA Phase III Study of BBI-608 plus nab-Paclitaxel with Gemcitabine in Adult Patients with Metastatic Pancreatic Adenocarcinoma.
DescriptionThis is a randomized, open-label, multi-center, phase 3 study of napabucasin plus weekly nab-paclitaxel with gemcitabine versus weekly nab-paclitaxel with gemcitabine for adult patients with Metastatic Pancreatic Ductal Adenocarcinoma.
Key EligibilityIn order to be eligible to take part in this trial, patients must meet the following criteria:

  • 18 years or older
  • Advanced pancreatic ductal adenocarcinoma (PDAC) that is metastatic
For a full list of participation criteria, please visit
Applicable Disease SitesPancreatic Cancer
Participating InstitutionsIU Health Central Indiana Cancer Centers
  • CICC Carmel
  • CICC East
  • CICC Fishers
  • CICC Methodist
Indiana University (IU)
  • Eskenazi Hospital
  • Indiana University Hospital / IU Simon Cancer Center
Treatment TypeTreatment
ContactPhone: (317) 278-5632