Clinical Trials

Find a Trial

Trial Summary

Protocol No.IUSCC-0586
Principal InvestigatorPaczesny, Sophie
Age GroupAdults and Children
TitleBiomarkers of endothelial dysfunction in pediatric patients receiving high intensity chemotherapy/irradiation
DescriptionThis study is designed to collect longitudinal biological samples from patients after hematopoietic cell transplantation (HCT) cared for at multiple bone marrow transplant centers to validate biomarkers of both acute and chronic GVHD as well as for use in future unspecified research. The centers include Dana-Farber Cancer Institute and Boston's Children's Hospital, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Fred Hutchinson Cancer Research Center, Texas Children's Hospital, Children's National Medical Center, and Indiana University Simon Cancer Center.
Key EligibilityIn order to be eligible to take part in this trial, patients must meet the following criteria:

  • All patients receiving an allogeneic hematopoietic stem cell transplant, cord blood transplant, bone marrow transplant, T cell depleted marrow, donor lymphocyte infusion (DLI), or donor cellular infusion (DCI) can be included.
For a full list of participation criteria, please visit
Applicable Disease SitesAny Site
Participating InstitutionsBaylor College of Medicine
  • Texas Children's Hospital
George Washington University
  • Children?s National Medical Center
Indiana University (IU)
  • Riley Hospital for Children
University of Michigan Health System
  • University of Michigan Health System
Treatment TypeOther
ContactMelissa Lee, Phone: +1 317-944-4281
Pager: 312-1228