Mahua Dey, M.D.
355 W 16th Street
Methodist GH 5100
Indianapolis, IN 46202
Phone: (317) 274-2601
Research Program Membership
Assistant Professor of Neurological Surgery
Department of Neurological Surgery
IU School of Medicine
As a surgical neuro-oncologist, I am interested in translational research involving malignant gliomas. Specifically I am interested in studying glioma associated immunosuppression and developing effective anti-glioma immunotherapy. During my post-doctoral studies I have shown that immunoregulatory plasmacytoid dendritic cells accumulate in glioma microenvironment and help propagate inhibitory regulatory T cells in the tumor microenvironment. Depletion of pDCs in transgenic mouse model results in survival advantage. In a vaccine model, depletion of pDCs and use of mature mDCs results in robust anti-glioma immune response. Moving forward I plan to dissect the mechanisms of pDC recruitment in glioma and advance the anti-glioma vaccine strategy to clinical trial.
Residency - The University of Chicago, Chicago, IL 2015
Post-doctoral Fellowship - The University of Chicago, Chicago, IL 2014
Post-doctoral Fellowship - MD Anderson Caner Center, Houston, TX 2008
M.D. - Baylor College, Houston, TX 2007