Member Biography


Mahua Dey, M.D.

980 W. Walnut St.
Rm C514
Indianapolis, IN 46202

Phone: (317) 274-2601
Fax: (317) 274-8046

Research Program Membership

Associate member

Assistant Professor of Neurosurgery
Department of Neurological Surgery
IU School of Medicine

As a surgical neuro-oncologist, I am interested in translational research involving malignant gliomas. Specifically I am interested in studying glioma associated immunosuppression and developing effective anti-glioma immunotherapy. During my post-doctoral studies I have shown that immunoregulatory plasmacytoid dendritic cells accumulate in glioma microenvironment and help propagate inhibitory regulatory T cells in the tumor microenvironment. Depletion of pDCs in transgenic mouse model results in survival advantage. In a vaccine model, depletion of pDCs and use of mature mDCs results in robust anti-glioma immune response. Moving forward I plan to dissect the mechanisms of pDC recruitment in glioma and advance the anti-glioma vaccine strategy to clinical trial.

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More Publications »

Residency - The University of Chicago, Chicago, IL 2015

Post-doctoral Fellowship - The University of Chicago, Chicago, IL 2014

Post-doctoral Fellowship - MD Anderson Caner Center, Houston, TX 2008

M.D. - Baylor College, Houston, TX 2007