Clark Wells, Ph.D.
635 Barnhill Drive
Indianapolis, IN 46202
Phone: (317) 278-1060
Fax: (317) 274-4686
Research Program Membership
Department of Biochemistry and Molecular Biology
IU School of Medicine
The long term goal of my laboratory is to understand how de-differentiation of mammary epithelial cells during breast cancer initiation and progression is coordinated with the loss of growth control. Specifically we are analyzing the interrelationship between protein sorting decisions and the maintenance or loss of differentiation. Particular focus is on the impact of changes in the expression of the adaptor protein Amot on tight junction integrity and the induction of HIPPO signaling that underlies aberrant cell growth and invasiveness.
Post-doctoral Fellowship - Mt. Sinai Hospital, Tornoto, Canada 2001-2006
Ph.D. - University of Texas Southwestern Medical School 2001