Baohua Zhou, Ph.D.
1044 W. Walnut St.
Phone: (317) 274-0308
Fax: (317) 274-5378
Research Program Membership
Associate Professor Associate Professor
Department of Pediatrics
IU School of Medicine
Department of Microbiology and Immunology
My lab focuses on a new cytokine thymic stromal lymphopoietin (TSLP) and its function in immunity and diseases. Studies from my lab, together with several others, established a critical role for TSLP in the pathogenesis of asthma and allergy. Recently, it has been demonstrated that TSLP also plays critical roles in the growth and metastasis of breast cancer, lung cancer and pancreatic cancer in both humans and mice. Using breast cancer cell line 4T1, we found that 4T1 cells express high levels of TSLP and curcumin suppressed TSLP expression. With the resources in my lab (both TSLP knockout and TSLP receptor knockout mice), we will move on to study the role of TSLP in progression of carcinomas. We will also collaborate with Dr. Mingjiang Xu, a newly recruited faculty in Hematologic Malignancies and Stem Cell Biology Research Group, Wells Center for Pediatric Research, to study the roles of TSLP in progression of leukemia. TSLP as a therapeutic target in cancer treatment will also be explored.
Post-doctoral Fellowship - Benaroya Research Institute, Seattle, WA 2000-2005
Ph.D. - University of Washington, Seattle, WA 2000