Funding Opportunities

NIH Funding Opportunities

Notice of the National Institute on Drug Abuse (NIDA) Participation in PAR-15-070 "Assay Development and Therapeutic Agent Identification and Characterization to Support Therapeutic Discovery (R21/R33)"
Notice NOT-DA-15-045 from the NIH Guide for Grants and Contracts
Tue, 24 Feb 2015 10:51:22 EST

Notice of the National Institute on Drug Abuse (NIDA) Participation in PAR-15-071 "Pharmacodynamics and In vivo Efficacy Studies for Small Molecules and Biologics/Biotechnology Products (R21/R33)"
Notice NOT-DA-15-046 from the NIH Guide for Grants and Contracts
Tue, 24 Feb 2015 12:46:10 EST

Notice of Correction to the Pre-Application Technical Assistance Webinar for the Adolescent Brain Cognitive Development (ABCD) Longitudinal Study Funding Opportunity Announcements Announced in NOT-DA-15-047
Notice NOT-DA-15-050 from the NIH Guide for Grants and Contracts
Mon, 23 Feb 2015 01:55:07 EST

Adding the Center for Drug Evaluation and Research (CDER) to PAR-14-237
Notice NOT-FD-15-002 from the NIH Guide for Grants and Contracts
Thu, 26 Feb 2015 11:58:23 EST

Request for Information (RFI) on NIGMS Programs to Enhance Diversity in the Biomedical Research Workforce
Notice NOT-GM-15-108 from the NIH Guide for Grants and Contracts
Tue, 24 Feb 2015 03:07:49 EST

Notice of Intent to Publish a Funding Opportunity Announcement for Developmental Mechanisms of Human Structural Birth Defects (P01)
Notice NOT-HD-15-002 from the NIH Guide for Grants and Contracts
Thu, 26 Feb 2015 01:43:43 EST

Request for Information (RFI): An Internet Resource for Placental Research - Placental Atlas Tool
Notice NOT-HD-15-005 from the NIH Guide for Grants and Contracts
Wed, 25 Feb 2015 05:34:40 EST

Notice to Terminate RFA-HD-15-032 "The Human Placenta Project: Developing Paradigm-Shifting Innovations for in vivo Human Placental Assessment (U34)"
Notice NOT-HD-15-006 from the NIH Guide for Grants and Contracts
Thu, 26 Feb 2015 01:36:41 EST

Notice of Clarification of Language in RFA-HG-15-001 "Centers for Common Disease Genomics (UM1)"
Notice NOT-HG-15-022 from the NIH Guide for Grants and Contracts
Wed, 25 Feb 2015 05:42:32 EST

Notice of Deadline Extension for NOT-OD-15-056 Request for Information (RFI): FY2016-2020 Strategic Plan for the Office of Research Infrastructure Programs: Division of Comparative Medicine and Division of Construction and Instruments Programs
Notice NOT-OD-15-070 from the NIH Guide for Grants and Contracts
Thu, 26 Feb 2015 01:32:53 EST

Notice of Deadline Extension for NOT-OD-15-055 "Request for Information (RFI): FY2016-2020 Strategic Plan for the Office of Research Infrastructure Programs: Office of Science Education/Science Education Partnership Award
Notice NOT-OD-15-071 from the NIH Guide for Grants and Contracts
Thu, 26 Feb 2015 01:56:29 EST

Notice of Extension of Public Comment Period for Notice of Proposed Rulemaking for Clinical Trials Registration and Results Submission under FDAAA
Notice NOT-OD-15-072 from the NIH Guide for Grants and Contracts
Thu, 26 Feb 2015 01:54:14 EST

Correction to Application Guide Instructions for Subawards Not Active in All Budget Periods of the Prime Applicant
Notice NOT-OD-15-073 from the NIH Guide for Grants and Contracts
Thu, 26 Feb 2015 01:38:59 EST

Big Data to Knowledge (BD2K) Advancing Biomedical Science Using Crowdsourcing and Interactive Digital Media (UH2)
Funding Opportunity RFA-CA-15-006 from the NIH Guide for Grants and Contracts. The purpose of this Big Data to Knowledge funding opportunity (FOA) announcement is to support the development of new or significantly adapted interactive digital media that engages the public, experts or non-experts, in performing some aspect of biomedical research via crowdsourcing. To be responsive to this FOA, each application is expected to pose a challenging biomedical research problem and propose the development of engaging interactive digital media that incorporates crowdsourcing as a fundamental component of how the problem is solved. The biomedical research problem should be amenable to one or more human computation approaches, as the users must be active participants in the analysis and/or interpretation of data, rather than acting primarily as data collectors or sources of data.
Mon, 23 Feb 2015 09:14:30 EST

Children's Health Exposure Analysis Resource (CHEAR): National Exposure Assessment Laboratory Network (U2C)
Funding Opportunity RFA-ES-15-009 from the NIH Guide for Grants and Contracts. NIEHS is establishing an infrastructure, the Children's Health Exposure Analysis Resource (CHEAR), to provide the extramural research community access to laboratory and statistical analyses to add or expand the inclusion of environmental exposures in their research. CHEAR is being solicited through three FOAs, this FOA solicits a network of laboratories providing a comprehensive suite of laboratory-based analytical services for samples derived from extant or ongoing children's health studies in the extramural research community. Each laboratory center (defined in this FOA as a Hub) within the network will provide analysis of environmental and endogenous exposures through both targeted and untargeted approaches. Each Hub will also provide analyses of biological response indicators such as DNA damage, oxidative stress, immune/inflammation indicators and other molecular markers. Hubs will incorporate a developmental core to develop novel measures for exposures and responses, expanding the number of current, commonly measured analytes, and developing new methods for detecting analytes in other biological matrices, in addition to serum, plasma or urine. The Children's Health Exposure Analysis Resource (CHEAR) is a multi-unit infrastructure to provide access to comprehensive exposure analysis that can be performed using biological samples collected in studies of children's health. The network has three units, a National Exposure Assessment Laboratory Network and an Exposure Data Repository and Resource for Statistical Analysis and Methods Development, as well as a coordinating center.
Thu, 26 Feb 2015 11:57:44 EST

Children's Health Exposure Analysis Resource (CHEAR): Data Repository, Analysis and Science Center (U2C)
Funding Opportunity RFA-ES-15-010 from the NIH Guide for Grants and Contracts. NIEHS is establishing an infrastructure, the Childrens Health Exposure Analysis Resource (CHEAR), to provide the extramural research community access to laboratory and statistical analyses to add or expand the inclusion of environmental exposures in their research.CHEAR is a multi-unit infrastructure to provide access to comprehensive exposure assessment for NIH funded studies of Childrens Health.CHEAR is being solicited through three FOAs, this FOA solicits a Data Repository, Analysis, and Science Center (Data Center) for CHEAR.The network has two units in addition to this Data Center, a National Exposure Assessment Laboratory Network and an overall CHEAR Coordinating Center. The Data Center will provide intellectual and logistical support for the maintenance, analysis, interpretation, curation, and reuse of data generated by CHEAR in support of extramural research projects.The Data Center will provide two distinct services to the extramural community.The Center will support statistical consultation and perform statistical analyses for studies using the CHEAR infrastructure including the development and dissemination of new statistical methods and informatics tools.In addition, the Data Center will develop and manage an exposure data repository and associated data science resources. The ultimate goal is maximizing potential use and impact of exposure data both within and outside of CHEAR.
Thu, 26 Feb 2015 02:06:52 EST

Children's Health Exposure Analysis Resource (CHEAR): Coordinating Center (U24)
Funding Opportunity RFA-ES-15-011 from the NIH Guide for Grants and Contracts. NIEHS is establishing an infrastructure, the Childrens Health Exposure Analysis Resource (CHEAR), to provide the extramural research community access to laboratory and statistical analyses to add or expand the inclusion of environmental exposures in their research.CHEAR is being solicited through three FOAs, this FOA solicits a Coordinating Center. In addition, FOAs are being released to solicit a National Exposure Assessment Laboratory Network and an Exposure Data Repository and Resource for Statistical Analysis and Methods Development. The CHEAR Coordinating Center (U24) will serve as the administrative hub and external access point for CHEAR, managing the flow of materials, data, and analyses between CHEAR units and participating investigators. In addition, the coordinating center will also support administrative functions such as convening steering committee and CHEAR meetings, and organize communication and outreach activities.
Thu, 26 Feb 2015 01:59:37 EST

Minor Use Minor Species Development of Drugs; Research Project Grant (R01)
Funding Opportunity RFA-FD-15-004 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is issued by the Food and Drug Administration (FDA), Center for Veterinary Medicine (CVM), and solicits Research Project (R01) grant applications from institutions or organizations that propose to develop, or support the development of new animal drugs intended for minor use in major species or intended for use in minor species. The FDA is authorized to provide grants only to assist in defraying the costs of qualified safety and effectiveness testing when a grant will either result in or substantially contribute to FDA approval or conditional approval of a new animal drug. Only companies developing drugs for veterinary use or parties working as research partners with such companies are eligible for grants. Only studies in support of new animal drugs that such companies have had designated for specified intended uses by FDA/CVMs Office of Minor Use and Minor Species Animal Drug Development (OMUMS), in accordance with the provisions of section 573 of the Food, Drug and Cosmetic Act (21 U.S.C. 360ccc-2) and 21 CFR part 516, are eligible for grants. Qualified studies eligible for funding include those intended to support target animal safety or effectiveness, environmental safety, or human food safety. The protocol for a proposed study must be accepted by FDA/CVMs Office of New Animal Drug Evaluation (ONADE) prior to application submission. In addition to studies intended to directly establish target animal safety or effectiveness, the following manufacturing studies supportive of target animal safety or effectiveness are eligible for funding, provided a protocol has been accepted by FDA/CVM/ONADE: A study to evaluate the stability of a MUMS drug A study to validate analytical methods associated with the manufacture of a MUMS drug A study to determine the homogeneity/segregation of an animal feed bearing or containing a MUMS drug A study to validate analytical methods for an animal feed bearing or containing a MUMS drug. In addition to studies intended to directly establish human food safety, a separate study to validate an analytical method prior to the conduct of an in-life human food safety study is eligible for funding, provided a protocol has been accepted by FDA/CVM/ONADE. Applicants must include an explanation of how the proposed study will contribute to FDA approval or conditional approval of the product in the applications Significance section of the Research Strategy (PHS 398 Research Plan). All funded studies are subject to the requirements of the Federal Food, Drug and Cosmetic Act (21 U.S.C. 331 et seq.), regulations issued under it, and applicable Department of Health and Human Services (HHS) statutes and regulations.
Thu, 26 Feb 2015 01:42:28 EST

Developing Paradigm-Shifting Innovations for in vivo Human Placental Assessment in Response to Environmental Influences (U01)
Funding Opportunity RFA-HD-15-034 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) in support of the Human Placenta Project (HPP) aims to support the initial stages of development of entirely new or next-generation placental imaging and assessment technologies and methods that will increase our capability to assess human placental structure and function safely in vivo throughout gestation and to explore the impact of environmental influences on placental structure and function across pregnancy.
Thu, 26 Feb 2015 09:58:12 EST

Eunice Kennedy Shriver NICHD Maternal-Fetal Medicine Units (MFMU) Network (UG1)
Funding Opportunity RFA-HD-16-019 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) invites applications from investigators willing to participate with the NICHD in clinical trials and observational studies under a cooperative agreement in an ongoing multi-center clinical program designed to investigate problems in perinatal medicine, particularly those related to low birth weight, prematurity, and common obstetrical medical problems.
Mon, 23 Feb 2015 09:02:49 EST

Eunice Kennedy Shriver NICHD Cooperative Multicenter Neonatal Research Network (UG1)
Funding Opportunity RFA-HD-16-020 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) invites applications from investigators willing to participate with the NICHD in clinical trials and observational studies under a cooperative agreement in an ongoing multi-center clinical program designed to investigate problems in neonatal medicine, particularly those related to low birth weight, prematurity, and common neonatal medical problems.
Mon, 23 Feb 2015 01:55:16 EST

Sudden Cardiac Death in the Young: Population Based Studies (U01)
Funding Opportunity RFA-HL-16-002 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to support mechanistic, genetic, and other studies to evaluate causes and consequences of and risk factors for sudden cardiac death in the young. Studies are required to use data and DNA samples from the Sudden Death in the Young Case Registry (described below) as foundations for their research.
Wed, 25 Feb 2015 05:15:13 EST

NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44)
Funding Opportunity RFA-HL-16-009 from the NIH Guide for Grants and Contracts. The purpose of the NHLBI SBIR Phase IIB Bridge Award is to facilitate and accelerate the capital-intensive steps that are required to transition SBIR/STTR Phase II projects to the commercialization stage by promoting partnerships between SBIR/STTR Phase II awardees and third-party investors and/or strategic partners. Applicants must submit a Commercialization Plan, which should include details on any independent third-party funding that has already been secured or is anticipated during the Phase IIB Bridge Award project period. It is expected that the level of this independent third-party funding will be equal to or greater than the NHLBI funds being requested throughout the Phase IIB Bridge Award project period. Projects proposed in response to this FOA must relate to the NHLBI mission and require eventual Federal regulatory approval/clearance. Proposed projects may address preclinical and/or clinical stages of technology development. Clinical trials may be proposed as appropriate, but are not required.
Wed, 25 Feb 2015 05:32:04 EST

Administrative Supplements for Common Basic Sociobehavioral Mechanisms and Processes that Facilitate or Impede Self-Management of Chronic Conditions (Admin Supp)
Funding Opportunity PA-15-122 from the NIH Guide for Grants and Contracts. NIH's Basic Behavioral and Social Science Opportunity Network (OppNet) announces the opportunity of funds to support increases in costs on existing projects in order to elucidate basic mechanisms and processes that facilitate and/or impede an individual's attitudes, beliefs, knowledge, and behaviors involved with the self-management of chronic disease conditions within respective social and/or physical environment(s).
Tue, 24 Feb 2015 10:26:45 EST

Collaborative Activities to promote High Dimensional Molecular Analyses in NIEHS-supported Children's Environmental Health Studies (Admin Supp)
Funding Opportunity PA-15-123 from the NIH Guide for Grants and Contracts. These administrative supplements provide funds to awarded research grants to facilitate or enhance ongoing efforts in proteomics, metabolomics, epigenomics and other high dimensional molecular analysis approaches in existing pregnancy, birth, and/or childrens cohorts.
Tue, 24 Feb 2015 10:45:54 EST

Early-life Factors and Cancer Development Later in Life (R03)
Funding Opportunity PA-15-124 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research focused on the role of early-life factors in cancer development later in life.Given that current emerging evidence from limited research indicates a potentially important role for early-life events and exposures in cancer development, it is necessary to better understand 1) the early-life (maternal-paternal, in utero, birth and infancy, puberty and adolescence, and teenage and young adult years) factors that are associated with later cancer development; 2) how early-life factors mediate biological processes relevant to carcinogenesis; and 3) whether predictive markers for cancer risk based on what happens biologically at early-life can be measured and developed for use in cancer prevention strategies. Markers that predict malignancy or pre-malignant conditions would allow assessment of early-life exposures with relevant outcomes without having to wait 50 years for cancer development. Ultimately, a better mechanistic understanding of how early-life events and exposures contribute to the etiology of cancer later in life will allow for the development of effective interventions during pregnancy or early life that may have a profound impact on cancer prevention.
Thu, 26 Feb 2015 01:51:50 EST

Early-life Factors and Cancer Development Later in Life (R21)
Funding Opportunity PA-15-125 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research focused on the role of early-life factors in cancer development later in life.Given that current emerging evidence from limited research indicates a potentially important role for early-life events and exposures in cancer development, it is necessary to better understand 1) the early-life (maternal-paternal, in utero, birth and infancy, puberty and adolescence, and teenage and young adult years) factors that are associated with later cancer development; 2) how early-life factors mediate biological processes relevant to carcinogenesis; and 3) whether predictive markers for cancer risk based on what happens biologically at early-life can be measured and developed for use in cancer prevention strategies. Markers that predict malignancy or pre-malignant conditions would allow assessment of early-life exposures with relevant outcomes without having to wait 50 years for cancer development. Ultimately, a better mechanistic understanding of how early-life events and exposures contribute to the etiology of cancer later in life will allow for the development of effective interventions during pregnancy or early life that may have a profound impact on cancer prevention.
Thu, 26 Feb 2015 01:49:44 EST

Early-life Factors and Cancer Development Later in Life (R01)
Funding Opportunity PA-15-126 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research focused on the role of early-life factors in cancer development later in life.Given that current emerging evidence from limited research indicates a potentially important role for early-life events and exposures in cancer development, it is necessary to better understand 1) the early-life (maternal-paternal, in utero, birth and infancy, puberty and adolescence, and teenage and young adult years) factors that are associated with later cancer development; 2) how early-life factors mediate biological processes relevant to carcinogenesis; and 3) whether predictive markers for cancer risk based on what happens biologically at early-life can be measured and developed for use in cancer prevention strategies. Markers that predict malignancy or pre-malignant conditions would allow assessment of early-life exposures with relevant outcomes without having to wait 50 years for cancer development. Ultimately, a better mechanistic understanding of how early-life events and exposures contribute to the etiology of cancer later in life will allow for the development of effective interventions during pregnancy or early life that may have a profound impact on cancer prevention.
Thu, 26 Feb 2015 01:46:52 EST

Advancing Translational and Clinical Probiotic/Prebiotic and Human Microbiome Research (R01)
Funding Opportunity PA-15-127 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is twofold: 1. to accelerate translational and clinical Phase I and II a/b safety and efficacy studies for substantiating measurable functional benefits of probiotic/prebiotic components and/or their combinations; and; 2. to understand the underlying mechanisms of their action(s), and variability in responses to these interventions. This FOA calls for interdisciplinary collaborations across scientific disciplines engaged in microbiome and pro/prebiotic research including, but not limited to: nutritional science, microbiology, virology, microecology and microbiome, genomics, immunology, computational biology, chemistry, bioengineering, as well as integration of omics and computational approaches in DNA technologies. This FOA will not support phase III clinical trials.
Thu, 26 Feb 2015 01:04:23 EST

One-Year Administrative Supplements to NIMH-supported Research for FY2015 (Admin Supp)
Funding Opportunity PA-15-128 from the NIH Guide for Grants and Contracts. The National Institute of Mental Health announces the availability of one-year administrative supplements to support on-going NIMH-supported research.Investigators with active NIMH-supported research grants can request supplemental funding in FY2015 for continued research in one of the NIMH identified priority areas.NIMH has identified specific areas of interest in accordance with its goal of accelerating mental health research as described in the Institutes Strategic Plan.
Fri, 27 Feb 2015 09:25:29 EST