Shared Facilities

Transgenic & Knock-Out Mouse


The services provided by the Transgenic & Knock-Out Mouse Core include:

  • The production of transgenic mice (via pronuclear injection of recombinant DNA molecules)
  • The production of knockout mice (via homologous recombination in ES cells)
  • Advice concerning construction of transgenic and gene targeting constructs, animal breeding and maintenance of the resulting mouse colonies