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Review

Marina N, Gebhardt M, Teot L, Gorlick R. Biology and therapeutic advances for pediatric osteosarcoma. Oncologist. 2004;9(4):422-41.

Saeter G; European Society for Medical Oncology. ESMO Minimum Clinical Recommendations for diagnosis, treatment and follow-up of osteosarcoma. Ann Oncol. 2003 Aug;14(8):1165-6.

"Osteosarcoma." Timothy P Cripe, MD, PhD. eMedicine Online

Chemotherapy

Goorin AM, Harris MB, Bernstein M, et al. Phase II/III trial of etoposide and high-dose ifosfamide in newly diagnosed metastatic osteosarcoma: a Pediatric Oncology Group trial. Journal of Clinical Oncology 2002, 20,426-433.

Bielack SS, Kempf-Bielack B, Delling G et al. Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols. J Clin Oncol 2002;20:776-790.

Bacci G, Ferrari S, Bertoni F: Long-term outcome for patients with nonmetastatic osteosarcoma of the extremity treated at the istituto ortopedico rizzoli according to the istituto ortopedico rizzoli/osteosarcoma-2 protocol: an updated report. J Clin Oncol 2000 Dec 15; 18(24): 4016-27[Medline].

Radiation

Ozaki T, Flege S, Kevric M et al. Osteosarcoma of the pelvis: experience of the Cooperative Osteosarcoma Study Group. J Clin Oncol 2003;21:334-341.

Metastatic osteosarcoma

Kager L, Zoubek A, Pötschger U, et al. Primary metastatic osteosarcoma: presentation and outcome of patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols. Journal of Clinical Oncology, 2003, 21, 2011-2018.

Late effects

Nicholson HS, Mulvihill JJ, Byrne J. Late effects of therapy in adult survivors of osteosarcoma and Ewing's sarcoma. Medical and Pediatric Oncology 1992, 20, 6-12.

Biology

Gorlick R, Anderson P, Andrulis I, Arndt C, Beardsley GP, Bernstein M et. al. Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary. Clin Cancer Res. 2003 Nov 15;9(15):5442-53.

Wang LL. Biology of osteogenic sarcoma. Cancer J. 2005 Jul-Aug;11(4):294-305.

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